9 in 10
parents are carriers for a genetic condition¹
70 million
people in India have a genetic condition²
2 in 3
couples are likely to have children at higher risk for at least one common disease³
One cheek swab.
[NUM_CONDITIONS_SCREENED]+ screenings.
And more
Genetic diseases, conditions
Is Preview
right for you?
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What is Nucleus Preview?
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Nucleus Preview is an advanced preconception genetic test, designed for couples. Through a simple cheek swab, it evaluates genetic conditions that may be passed on to future children, including cancers, heart disease, diabetes, sickle cell, and endometriosis.
It provides a broader view than traditional genetic tests, helping you and your care team understand and plan earlier with more information.
What genetic insights will Preview give me?
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Preview helps you understand what potential genetic conditions are relevant to your future child, including:
Rare inherited conditions, like cystic fibrosis and spinal muscular atrophy (SMA)
The probability of risk for common conditions, like heart disease and Alzheimer’s disease
You’ll also receive insights into your own health.
How is Preview different from what's offered in clinics?
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Preview gives you a deeper look into what genetic conditions you should discuss with your doctor, evaluating 2,000+ disease risks. It’s directly available to prospective parents, but it’s also a clinical-grade genetic test that’s already used in many IVF clinics too.
Most traditional preconception genetic tests (often called carrier screening) focus on a defined set of serious single-gene conditions and diseases that both parents are carriers for. That matters, but it doesn’t reflect the full range of questions many parents have today. Many significant conditions like hereditary breast and ovarian cancer (HBOC) and Lynch syndrome have a 50% chance of being passed on, even if only one parent has it.
Preview includes that rare disease screening focused on both partners and expands beyond it.
It estimates likelihood for common health risks that either parent could be a carrier for like cancer, diabetes, and heart disease.
How can Preview tell me about things like diabetes or cancer?
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Preview looks at your DNA to understand genetic patterns linked to common conditions like diabetes, heart disease, and many cancers.
Unlike rare diseases that are caused by a single gene, most common health conditions are influenced by many genes working together. So instead of searching for one rare mutation, Preview looks at lots of small genetic factors that, together, shape likelihood.
Do I need a partner to do Preview?
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It helps, but you don’t have to. You can do Preview on your own to understand what you might pass on. If a partner tests too (even later on), you can easily pair your results and see the combined genetic picture, which is the most complete view.
Do I have to be doing IVF to do Preview?
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Not at all. Many couples do Preview as their first step in family planning, whether IVF is already in the cards for them, or they’re hoping to conceive naturally. The goal is to get more information at the earliest point, so you can take steps to reduce risk and make decisions that support your future child’s long-term health.
Is Preview available to order internationally?
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Shipping is available for certain Nucleus products to India, the United States, Canada, the United Kingdom, Ireland, Germany, Switzerland, Spain, Italy, and the United Arab Emirates.
The New England Journal of Medicine. Nationwide, Couple-Based Genetic Carrier Screening
Percent calculated based on parents together being at above average risk for at least one of 15 common diseases.
